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Enzyme Biocatalysis R&D at Prozomix

In-house R&D at Prozomix is focused towards next-generation Enzyme Biocatalysis technologies.


Prof. Simon J. Charnock
Managing Director / Technical Director

Visiting Professor at Northumbria University Newcastle

Experience: biocatalysis, molecular biology, enzymology, macromolecular structural biology, biochemistry, analytical biochemistry, protein chemistry, enzyme discovery, advanced recombinant enzyme technology, biocatalyst development, commercialisation

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Contact: simon.charnock@prozomix.com

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Dr Ruth M. LloydOperations Director

Experience: molecular biology, biochemistry, analytical biochemistry, enzyme biocatalysis, protein commercialisation, product pipeline management

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Contact: ruth.lloyd@prozomix.com

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Dr Yuyin Qi – Senior Research Scientist / Research Laboratory Manager

Current research focuses on use of GRASP HT-metagenome-mining technology towards discovery and characterisation of 1000s of novel aldolases as part of the H2020 project CARBAZYMES.

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Dr Darren Cook – Senior Research Scientist / Project Manager

Current research focuses on discovery of novel P450s and other oxidases as part of the FP7 project BIOOX.  Project Management of numerous Innovate UK, FP7 and H2020 projects, in addition to collaborations with both academia and industry.

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Dr Jesmine Lim – Senior Research Scientist

Current research focuses on development of advanced in-house metagenome-mining technology (meta-GRASP) towards significantly increasing both the diversity and number of biocatalysts presented in the Prozomix Biocatalysis Enzyme Toolkit.

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Dr Kirsty Graham  Senior Research Scientist

Current research focuses on discovery and development of large novel panels of biocatalysts including transaminases and decarboxylases as part of a collaborative Innovate UK funded project with Northumbria University Newcastle.

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Richard Duncan  Research Scientist

Current research focuses on biocatalyst cloning, production, formulation, stabilisation and biochemical characterisation as part of the KYROBIO EU FP7 project.

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Kieron Petrusow – Research Scientist

Current research focuses on application of advanced bioinformatics towards novel enzyme discovery including execution of KRED10K, a project that will see the cloning of 10000 KRED encoding genes identified from in-house metagenomes.

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James Finnigan  PhD Student (Prozomix / NU Funded; 2014-2017)

Research Project: "Rational genome / metagenome mining towards population of a diverse panel of novel P450s“ as part of the BIOOX FP7 project.

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Samantha Gittings PhD Student (Prozomix / NU Funded; Sept 2016-Aug 2019)

Research Project: “Novel Enzyme Panel Development / Optimisation for Future Applied Biocatalysis Applications”.  Currently Samantha is a Research Scientist performing collaborative R&D in conjunction with Northumbria University Newcastle towards the development of a novel continuous-flow recombinant protein fermentation process.  Samantha's PhD studies at Prozomix will commence September 2016. 

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James Marshall  Sandwich Student from the University of Newcastle upon Tyne

Current research focuses on discovery of novel biocatalysis enzymes to populate 10 novel panels of biocatalysts via a collaborative Innovate UK funded project (TSB 131839) with Northumbria University Newcastle.

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Edward Shaw  Sandwich Student from the University of Newcastle upon Tyne

Current research focuses on application of in-house metagenomics towards novel KRED discovery for API synthesis with subsequent protein engineering for optimal biocatalyst generation.  This is a collaborative project funded by Innovate UK and performed in conjunction with CatScI Limited.

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