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» NAD(P)H Oxidase

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  • Cat No.
    Size
    Price
    Qty
     
  • PRO-NOX(001)-50mg
    50mg
    50.00
  • PRO-NOX(001)-1g
    1g
    450.00
  • PRO-NOX(001)- 10g
    10g
    1,550.00
  • PRO-NOX(001)-100g
    100g
    4,500.00
  • PRO-NOX(001)-1kg
    1kg
    9,900.00
  • PRO-NOX(001)-Bulk-enquire
    Bulk-enquire
    0.00

Catalogue No.:
PRO-NOX(001)

Product Name:
NAD(P)H Oxidase

Pack Size:
Freeze-dried CFE powder - 50 mg, 1 g, 10 g, 100 g, 1 kg, bulk.


Information:

PRO-NOX(001) is a dual functional NAD(P)H oxidase (NOX) suitable for the regeneration of both NAD+ and NADP+ during oxidative biotransformation syntheses, such as during alcohol oxidations according to equations (i) and (ii): 

    

                                        (KRED/AKR/ADH)

(i)                  2 alcohol   +   2 NAD(P)+   ®   2 ketone / aldehyde   +   2 NAD(P)H   +   2 H+

  

                                                    (NOX)

(ii)                 2 NAD(P)H   +   2 H+   +   O2   ®   2 NAD(P)+   +   2 H2O

 

NOX enzymes are particularly suited to biocatalysis applications, as they do not employ substrates or generate products that complicate subsequent work-up, resulting in decreased cost and/or increased purity and yield. PRO-NOX(001) is particularly suitable enzyme for the regeneration of NAD+ and NADP+, as it produces water, rather than hydrogen peroxide (H2O2), along with the oxidised cofactor (vide supra).  Hydrogen peroxide can inactivate or otherwise interfere with enzyme catalysed reactions, and would require removal using an additional enzyme such as catalase during scaled synthesis reactions.