» Oleandomycin glycosyltransferase
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Catalogue No.:
PRO-E0065
LOT:
2008-0065
Source Organism:
Streptomyces antibioticus
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PDF Downloads
- Product Specification Sheet
- Material Safety Data Sheet
EC No.:
2.4.1.-
Synonyms:
Macrolide glycosyltransferase
Nomenclature:
CAZy [GT1, glycosyltransferase family 1, member of fold GT-B], UGT102A2, OleD
Specific Activity:
NOTE: this product has been produced and is awaiting assay. It is thus currently available for purchase by the mg only
Accession No.:
CAA80301, Q53685
Molecular Weight:
47136.2 Da
Biological Function:
Glycosylation and thus inactivation of the macrolide antibiotic oleandomycin as an essential part of the host cell antibiotic immunity system of Streptomyces antibioticus. Unlike OleI from the same organism, OleD will also glucosylate other macrolides including tylosin and erythromycin
Comments:
PDB: 2IYF
MTTQTTPAHIAMFSIAAHGHVNPSLEVIRELVARGHRVTYAIPPVFADKVAATGPRPVLYHSTLPGPDAD PEAWGSTLLDNRRTFLNDAIQALPQLADAYADDIPDLVLHDITSYPARVLARRWGVPAVSLSPNLVAWKG YEEEVAEPMWREPRQTERGRAYYARFEAWLKENGITEHPDTFASHPPRSLVLIPKALQPHADRVDEDVYT FVGACQGDRAEEGGWQRPAGAEKVVLVSLGSAFTKQPAFYRECVRAFGNLPGWHLVLQIGRKVTPAELGE LPDNVEVHDWVPQLAILRQADLFVTHAGAGGSQEGLATATPMIAVPQAVDQFGNADMLQGLGVARKLATE EATADLLRETALALVDDPEVARRLRRIQAEMAQEGGTRRAADLIEAELPARHERQEPVGDRPNVGDRPAG VRSDRQRSAL


















