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» Oleandomycin glycosyltransferase

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  • Catalog #
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    Price
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  • PRO-E0065-1 mg
    1 mg
    £10.00
  • PRO-E0065-10 mg
    10 mg
    £70.00
  • PRO-E0065-100 mg
    100 mg
    £450.00
  • PRO-E0065-1 g
    1 g
    £2,700.00

Catalogue No.:
PRO-E0065

LOT:
2008-0065

Source Organism:
Streptomyces antibioticus

Enzyme Properties


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EC No.:
2.4.1.-

Synonyms:
Macrolide glycosyltransferase

Nomenclature:
CAZy [GT1, glycosyltransferase family 1, member of fold GT-B], UGT102A2, OleD

Specific Activity:
NOTE: this product has been produced and is awaiting assay. It is thus currently available for purchase by the mg only

Accession No.:
CAA80301, Q53685

Molecular Weight:
47136.2 Da

Biological Function:
Glycosylation and thus inactivation of the macrolide antibiotic oleandomycin as an essential part of the host cell antibiotic immunity system of Streptomyces antibioticus. Unlike OleI from the same organism, OleD will also glucosylate other macrolides including tylosin and erythromycin

Comments:
PDB: 2IYF

Primary Sequence


MTTQTTPAHIAMFSIAAHGHVNPSLEVIRELVARGHRVTYAIPPVFADKVAATGPRPVLYHSTLPGPDAD
PEAWGSTLLDNRRTFLNDAIQALPQLADAYADDIPDLVLHDITSYPARVLARRWGVPAVSLSPNLVAWKG
YEEEVAEPMWREPRQTERGRAYYARFEAWLKENGITEHPDTFASHPPRSLVLIPKALQPHADRVDEDVYT
FVGACQGDRAEEGGWQRPAGAEKVVLVSLGSAFTKQPAFYRECVRAFGNLPGWHLVLQIGRKVTPAELGE
LPDNVEVHDWVPQLAILRQADLFVTHAGAGGSQEGLATATPMIAVPQAVDQFGNADMLQGLGVARKLATE
EATADLLRETALALVDDPEVARRLRRIQAEMAQEGGTRRAADLIEAELPARHERQEPVGDRPNVGDRPAG
VRSDRQRSAL